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Principal Name: Adiponectin Receptor 2 (ADPR) 2 (human) C-Terminus: aa 362-380

$295.00


Code: CI0169

Synonyms: Adiponectin Receptor 2,  ADPR


  CE0169:  Antibody to human ADPR2 receptor C-terminus aa 362-380 on paraffin section of human liver (above) and on paraffin section of human muscle (below).

Specifications   print
Amount: 200 ug
Host: Goat
Antigen: Synthetic peptide (HFHGVSNLQEFRFMIGGGC) corresponding to aa 362-380 of the C-terminal domain of Human, Mouse and Rat ADPR 2 Receptor
Purification: Affinity Purification
Species Reactivity:
Human Monkey Mouse Rat
Buffer & Formulation: Liquid. 200 ug of peptide affinity purified IgG in PBS pH 7.2 at 1.0mg/ml with 1 mg/ml BSA and 0.1% sodium azide
Storage: Freeze at -80 °C. Stable for at least 3 years when stored at -80 °C.
Clone:
Applications
ELISA:
Western Blotting:
1: 1,000
IHC:
1: 250
Immunoprecipitation:
Flow Cytometry:
Comments:
Recognizes Human, Rat, Mouse and Macaca ADPR2 Receptor.  May cross-reacts to ADPR1 Receptor.  May be used in developing sandwitch ELISA assays in combination with antibodies specific to N-Terminus of ADPR2 Receptor

ADPR2 Sequence similarity between human, rat, mouse, Xenopus laevis, and Human ADPR1:
HFHGVSNLQEFRFMIGGGC  362-380 ADPR2 Human
HFHGVSNLQEFRFMIGGGC  362-380 ADPR2 Rat  
HFHGVSNLQEFRFMIGGGC  362-380 ADPR2 Mouse
HFHGVSNLQEFRYTVGGGC    361-379 MGC85478[Xenopus laevis]
HFYGVSNLQEFRYGLEGGC    351-369 Human ADPR1


References:
Yamauchi,T. et.al , Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Nature 423 (6941), 762-769 (2003)    Abstract

Staiger,H. et.al,  Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.  Diabetes 53 (9), 2195-2201 (2004)   Abstract

id#: 850

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